Epigenetics change which genes are active and which are inactive. Research over the past few years has shown that these changes are important for protecting the brain from neurodegeneration and injury. A review paper came out on May 18th in the journal Nature Reviews Neuroscience that summarizes this research. Check out the infographic for a description of the review paper.
Is consciousness everywhere? Is it a basic feature of the Universe, at the very heart of the tiniest subatomic particles? Such an idea – panpsychism as it is known – might sound like New Age mysticism, but some hard-nosed analytic philosophers have suggested it might be how things are, and it’s now a hot topic in philosophy of mind.
The brain is one of the most complex and amazing structures in the universe. It allows us to experience the world, feel, remember, and plan for the future. But for at least one organism, the brain is only a means to an end. Learn more in the infographic below!
Common sense tells us that only living things have an inner life. Rabbits and tigers and mice have feelings, sensations and experiences; tables and rocks and molecules do not. Panpsychists deny this datum of common sense. According to panpsychism, the smallest bits of matter – things such as electrons and quarks – have very basic kinds of experience; an electron has an inner life.Continue reading
In Part II of this series, we considered artificial intelligent in the context of Arthur C. Clarke’s novel and Stanley Kubrik’s film 2001: A Space Odyssey. In Space Odyssey, intelligence is arguably seen as an end in-and-of itself, rather than a means to an end. Flowers for Algernon, a short story later turned into a novel by author Daniel Keyes, questions that assumption while considering the ethical implications of artificially manipulating a person’s intelligence.
The protagonist of Flowers for Algernon is Charlie Gordon, a janitor who begins the story with intellectual disability, or mental retardation as it was referred to at the time when Keyes wrote the story. Gordon’s intellectual disability is a result of phenylketonuria, a real life metabolic disorder resulting from mutations of the gene encoding phenylalanine hydroxylase, an enzyme that breaks down the amino acid phenylalanine. An inability to metabolize this amino acid causes its toxic build up in the brain, often resulting in a low IQ and other problems, such as mental disorders.
In our previous post, we considered the Philip K. Dick novel Do Androids Dream of Electric Sheep? in the context of a thought experiment: a thinking tool used by scientists and philosophers to reframe an unintuitive problem in a new, more familiar context.
Another great thought experiment of the 1960s is 2001: A Space Odyssey. Developed in parallel as both a novel by Arthur C. Clarke and a film by Stanley Kubrick, Space Odyssey is a story about the evolution of humanity and intelligence. Beginning with the invention of tool use in Africa, the story asks how intelligence might continue to evolve after humans develop sophisticated technology. Both the novel and the film follow astronaut Dave Bowman on his journey to the Outer Solar System guided by HAL 9000, an artificial intelligence (AI) that controls the spaceship and is responsible for the well being of the crew.
It’s easy to find information on the internet — especially information that confirms what you already believe to be true. Through search engine bias, your Facebook newsfeed bubble, and confirmation bias, we can unknowingly surround ourselves with a cozy blanket of comforting information. Whether or not this information is true, however, is a different story. Check out this infographic for some strategies for how to know if what you’re reading is true.Continue reading
Let’s imagine something crazy.
What if each person in China was ordered to simulate a neuron in a brain, making an enormous “China brain?” Every participant in this grand experiment would be given a two-way radio to communicate with other people, similar to how neurons talk to each other. Some people play the role of “effector neurons,” which control parts of a giant robot, just as motor neurons in our nervous system control bodily movements.
Basically, imagine that the entire nation of China became a giant robot’s brain. What might happen?
The human brain is arguably the most complex organ. Throughout life, it is shaped ever so slightly by each and every experience we endure. The resulting nuances are what make us unique individuals. Unfortunately, the more intricate the system, the harder it is to fix when damaged. Death of any brain tissue will almost certainly result in some sort of physical or cognitive impairment, and, in severe cases, epilepsy, coma, or death. This is because the lost brain tissue can neither grow back like skin nor be replaced like a kidney.
Or can it?
America feels like it’s unraveling.
And science is holding on by a thread.
Benjamin Franklin once quipped: ‘There are three things extremely hard: steel, a diamond, and to know oneself.’ Every decision we make, from pinpointing the source of a faint sound to choosing a new job, comes with a degree of confidence that we have made the right call. If confidence is sufficiently low, we might change our minds and reverse our decision. Now scientists are using these choice reversals to study the first inklings of self-knowledge. Changes of mind, it turns out, reflect a precisely tuned process for monitoring our stream of thoughts.Continue reading
Given its subjective nature, consciousness is already a controversial topic in the world of brain science. While some neuroscientists doubt that consciousness can even be studied, others still endeavor towards identifying parts of the brain that support subjective awareness. At a gathering of neuroscientists February 15 in Bethesda, Maryland, an announcement has thrust the quest to understand consciousness into the spotlight once again. A team of neuroscientists lead by Christof Koch has identified neurons in a relatively obscure brain region known as the claustrum that send fibers far throughout the entire cerebral cortex, well beyond where they are expected to project. One neuron shown in the presentation engulfed the brain like a “crown of thorns” with its colossal fibers. According to Nature News, “Koch sees this as evidence that the claustrum could be coordinating inputs and outputs across the brain to create consciousness.”
The first human magnetic resonance imaging (MRI) scan was acquired almost 40 years ago. The scanner — hand-built by Dr. Raymond Damadian with the help of his two postdoctoral fellows — took nearly five hours to produce one snapshot of the human chest, and Dr. Damadian was eventually awarded the National Medal of Technology for his accomplishment.
If you ever gotten glitter on you, then you know that you will inevitably continue to find glitter on you many days after you’ve washed and showered.
Take a moment to think about what that means about the germs that get on your skin…
Well, not entirely.
Sometimes it’s hard to understand why scientists do what they do. Why spend a career studying cells, fungus, or flies? Other than being nerdy and wanting to learn about our world, what’s the point?Continue reading
Every March, Brain Awareness Week (BAW, for short) unifies the world in celebration of the brain and mind! In order to raise awareness about how the brain works, what neuroscientists do, and how amazing new research is, scientists present interactive activities, host laboratory tours, and speak to audiences about brain-related topics.
This year, we put together a list of our favorite Knowing Neurons content that highlight how amazing the brain is! Check them out and share the awesomeness!Continue reading
The evening of November 9th, 1938, began with typical fall solemnity for many Jews living across Germany: closing up their shops and businesses, returning home from school, and preparing family suppers. It would end with terror, as mobs ransacked storefronts, assaulted Jews on the street, and set fire to their homes. That terrible night would be known to history by the glittering debris of shattered windows lining the streets: “Kristallnacht.”
Kristallnacht, and the subsequent atrocities of Germany’s holocaust against the Jews, changed the world. Modernity had to forever acknowledge a surprising and abhorrent crime. Societies would undergo lasting changes, attempting to prevent such crimes, and the victims themselves, sadly, would suffer long-lasting impacts to their psyche.Continue reading
What would happen if you stuck your body inside a particle accelerator? The scenario seems like the start of a bad Marvel comic, but it happens to shed light on our intuitions about radiation, the vulnerability of the human body, and the very nature of matter. Particle accelerators allow physicists to study subatomic particles by speeding them up in powerful magnetic fields and then tracing the interactions that result from collisions. By delving into the mysteries of the Universe, colliders have entered the Zeitgeist and tapped the wonders and fears of our age.Continue reading
Sheldon Cooper, a beloved character in a television series, knocks on a door exactly three times before his roommate opens it — and if the door is opened earlier, he still persists his triad of door knocks. He fixates on occupying the exact same spot on the sofa every single time calling it “his” spot. As an audience, we watch his actions and surmise, “He has a little bit of OCD.”
The reality is: there is no such thing as a “little bit” when it comes to obsessive-compulsive disorders.Continue reading
Our thoughts are often mysterious to us. You probably don’t know why you suddenly think about a Komodo dragon while sitting in traffic or Citizen Kane while shopping for groceries. Such moments remind us that we are each the emergent property of an amazingly complex organ that never stops surprising us. Nonetheless, we usually feel in control of our thoughts. Even with the occasional unexpected thought, life continues as normal.Continue reading
From that evil itch on your arm to torturous diseases such as malaria, Zika, dengue, and yellow fever, mosquito bites can have unpleasant consequences. But have you ever wondered why those skin-diving insects are so good at detecting humans? Not so surprisingly, the answer lies in neuroscience — in a special field called chemosensation, the sensing of chemical stimuli.Continue reading
On January 6, 1995, a large five-foot-six 270-pound middle-aged man robbed two Pittsburgh banks in broad daylight. He didn’t wear a mask or any sort of disguise. And he smiled at surveillance cameras before walking out of each bank.
Later that night, police arrested a surprised McArthur Wheeler. When they showed him the surveillance tapes, Mr. Wheeler stared in disbelief. “But I wore the juice,” he mumbled.Continue reading
Would you trust a memory if it felt as real as all your others? And other people confirmed they remember it, too? What if the memory turned out to be false?Continue reading
A kid stealing candy in a convenience store grows up to be a convicted criminal. A husband who flirts with a coworker ends up as a serial cheater. A politician telling a few “white lies” to his or her constituents is eventually convicted of fraud. These are all extreme — but plausible — scenarios where dishonesty might escalate over time, resulting in dramatic and life-changing consequences. But how far does this slippery slope actually go? How can science help us answer this question?Continue reading
The pursuit of science is challenging. It is where new knowledge is born. In their path towards the unknown, scientists, too, face their fair share of insecurity. When experiments fail, grants evade, confidence dwindles and the clock strikes midnight, many researchers find themselves immersed in questions to which Google may not have an answer. What should I do after I graduate? Is there a glass ceiling for women? Is academia right for me? What other options are out there? Can I really get my act together for a work-life balance, like, ever? Sigh, these investment bankers make so much more money. What am I doing with my life? Maybe I should sleep now?Continue reading
The octopus almost reaches alien status when it comes to its brain and nervous system. And yet, the differences can help us understand more about the human brain as well as unique solutions nature has come up with for difficult problems like camouflage. Octopuses can see polarized light, but cannot see color. However, their skin changes both color and texture to camouflage with the surroundings.Continue reading
Brain stimulation might sound like some Frankensteinian demonstration from a Victorian science fair. But in reality, it is a contemporary technique making a huge impact in neuroscience by addressing a longstanding limitation of traditional methods for investigating human brain function. Such techniques, like EEG and fMRI, can only be used to infer the effects of a stimulus or task on brain activity, and not vice versa. For example, a scientist might use EEG to study the effect of a task like arm movement on brain activity, but how can one study the effect of brain activity on arm movement?Continue reading
Knowing Neurons had an amazing year, and we are so thankful for all your support throughout our journey! Here are some highlights from 2016!Continue reading
You’re on your way to the traditional Thanksgiving family get-together. You drive down a familiar street, locate your familiar house, and park in a familiar spot.Continue reading
Last month, on the big island of Hawaii, I swam with giant, beautiful aliens. Or at least that’s what it felt like. I went night snorkeling with manta rays and had the privilege of seeing 10 or 11 graceful behemoths. Some had a wingspan of over 10 feet long. Before our group got in the water, to prepare us for what we were about to see, our guide reassured us that manta rays are like sharks, but only the good parts, none of the scary parts. They don’t have teeth, they only eat plankton, and they have no stinger like their sting ray counterparts.Continue reading
When babies are born, they cannot see very well, but their vision vastly improves as they continue to develop. Sometimes, the eyes don’t communicate well with the brain, and vision disorders like amblyopia result. What are the neural mechanisms that allow normal visual development? What happens when things go amiss? And how can these disorders be prevented and treated? These are the questions that get Professor Lynne Kiorpes up in the morning! Listen to her passion as she explains her research and life as a neuroscientist:Continue reading
What does eye-witness identification have to do with neuroscience? A lot, actually.Continue reading
In a recent presidential town hall, President Obama looked directly into the camera and made a powerful statement about mental health. “If something inside you feels like it’s wounded, it’s just like a physical injury. You’ve got to go get help,” said the leader of the free world.
Buried under the weight of a massive social stigma, seeking help or even acknowledging a mental illness can be an excruciating task. How, then, can we help ourselves and our loved ones achieve emotional and mental well-being?Continue reading
We are excited to announce that we received the Society for Neuroscience 2016 Next Generation Award. This award recognizes SfN chapter members who have made outstanding contributions to public communication, outreach, and education about neuroscience. To celebrate the award reflecting our dedication to neuroscience education, we, the team members of Knowing Neurons, reminisce over some of their favorite moments in the past year.Continue reading
Everyone knows sharks are fierce predators. How exactly they hunt so well is in part due to their extra sixth sense: electroreception!Continue reading
Cute things are usually vulnerable, fragile and weak. But cuteness itself is mighty indeed. Morten L. Kringelbach and his colleagues at the University of Oxford recently described cuteness as ‘one of the most basic and powerful forces shaping our behavior.’ And yet, despite its elemental importance, cuteness might be a fluid, evolving concept and trait.Continue reading
Consider three scenarios. A kid joins a new high school and eats lunch by herself. A recently separated man is alone for the New Year’s Eve countdown. A prisoner becomes aggravated in a solitary confinement cell. The common thread that runs through these disparate experiences is the universal feeling of loneliness.Continue reading
It is no surprise that a child prefers its mother’s voice to those of strangers. Beginning in the womb, a fetus’s developing auditory pathways sense the sounds and vibrations of its mother. Soon after birth, a child can identify its mother’s voice and will work to hear her voice better over unfamiliar female voices. A 2014 study of preterm infants showed that playing a recording of the mother’s voice when babies sucked on a pacifier was enough to improve development of oral feeding skills and shorten their hospital stay. A mother’s voice can soothe a child in stressful situations, reducing levels of cortisol, the stress hormone, and increasing levels of oxytocin, the social bonding hormone. Scientists have even traced the power of a mother’s voice to infants’ brains: a mother’s voice activates the anterior prefrontal cortex and the left posterior temporal region more strongly than an unfamiliar voice, priming the infant for the specialized task of speech processing.
While it makes intuitive sense that a mother’s voice has special power over infants and toddlers, what happens as children grow up? Continue reading
Marine mammals, such as dolphins, whales, and porpoises, spend their entire lives at sea. Like us, they need to breathe, avoid danger, and care for their young. Like us, they need to sleep, which — for us — involves almost total unconsciousness and paralysis. So how do these marine mammals not drown when they sleep?Continue reading
My father often jokes that hundreds of years from now, future anthropologists will speak of the cult of the Seattle goddess, her shrine adorning every airport, shopping mall, and train station in America. The worshippers partake in a holy communion of coffee, tea, and espresso. In fact, anthropologists today tell us that in some indigenous American cultures, drinking psychoactive peyote tea is an important part of religious ceremony. And yet, the very phrase psychoactive tea is somewhat redundant. All tea and coffee, unless decaffeinated, is psychoactive, albeit usually not to the same extent as peyote, a cactus native to the American Southwest that contains a hallucinogenic alkaloid called mescaline.Continue reading
Our sense of sight is arguably our most important sense. Imagine how different your life would be if soon after birth, you lost the ability to see. For over 1.4 million children worldwide, that is their life. Being blind in developing countries like India has a costly impact: over 90% of blind children do not go to school, less than 50% make it to adulthood, and for those that do, only 20% are employed. But the real tragedy is that many of these cases of childhood blindness are completely avoidable and even treatable.
Why do they go untreated?
The human genome consists of nearly 25,000 protein-coding genes – and a mutation in just one of these can have dramatic effects on our brains. Remarkably, one tiny change in our genes (which can be as small as 0.000000025 cm!) can lead to visible changes in our behavior. Schizophrenia, autism, bipolar disorder, and ADHD have all been linked to variations in our DNA. But how do changes in our genetic code result in these complex psychiatric disorders?Continue reading
The jewel wasp’s venom is potent on two levels. Continue reading
The minds of individuals are like parallel universes, forever inaccessible to one another. Never do we truly see through the eyes of another person. It is common for us to wonder if other people experience the world in the same way we do. Is your green my red? Is my yellow your blue?Continue reading
Have you ever wondered if you experience the world like everyone else? We assume that our senses tell us what’s going on in the world, but they’re far from perfect. Synesthesia is a cool example of when our senses have a mind of their own.Continue reading
We have someone new joining our team! She is a neuroscience PhD student at the University of Iowa, and she studies speech perception – but let’s let the animation she created explain exactly what that means:Continue reading
If you grew up with siblings, it is likely that you have heard the phrase, ”Imitation is the sincerest form of flattery.” However, it wasn’t until a groundbreaking finding in the 1990s that the neural correlate to imitation was discovered in a class of neurons called mirror neurons. Continue reading
Responding to the assertion that computers lack intuition, the philosopher and cognitive scientist Daniel Dennett once (counter-intuitively) argued that computers must have intuition. Ask a computer to calculate the square root of 54357.029. How did the computer get the answer? Lacking awareness, the computer doesn’t know. The answer wasn’t the result of deep thinking or concentration. It was intuition.Continue reading
Your brain is the most remarkable thing about you because it makes you you. So, when Dean Burnett, Ph.D. chose to describe all that the brain does to make you amazing, he did it in a uniquely humane and entertaining way. His popular science book Idiot Brain: What Your Head is Really Up To is well-researched, well-written, and highly recommended for anyone interested in learning about how the brain works, fails to work, and even works against you.Continue reading
In Dante’s Inferno, the fifth circle of Hell is a place where the wrathful fight each other for eternity. Similarly, I often consider YouTube comments to be an extracanonical circle of Hell where the trolls fight each other for eternity. You might, then, imagine my surprise when I found many thoughtful comments expressing wonder and intrigue on a YouTube video of brain activity in a zebrafish. Continue reading
I would like to express my upmost gratitude for the vast amount of receptors you possess. Among my favorites – the practical ones that allow me to find keys at the bottom of my large jet-black bag, the emergency ones that warn me the fajita plate is searing, and those truly special ones that enable me to feel my lover’s caress and help me achieve orgasm…Continue reading
This weekend, I attended a special event at NASA’s Jet Propulsion Laboratories in Pasadena, CA to celebrate the Juno spacecraft’s July 4th arrival at the planet Jupiter. Planetary scientists study outer space, while neuroscientists such as myself study inner space. But as my visit to JPL revealed, the goals and challenges of each discipline are far more similar than you might think. So, what is Juno, and how does its mission mirror that of many neuroscientists?Continue reading
Our eyes contain millions of color-sensitive cells, called cones, which maximally respond to red, green, and blue light. With just these three types of color receptors, we can see the full rainbow of our world.Continue reading
The nostrils of a rabbit may seem like an unusual path to studying the nature of meaning and chaos. But Walter J. Freeman III was not a usual man. His father, Walter J. Freeman II, helped to popularize the frontal lobotomy in America, a procedure unthinkable by today’s ethical sensibilities. Continue reading
Welcome to Knowing Neurons’ Neuroscience Fiction Theater. Please note that the following story contains mild profanity and may be unsettling for younger audiences. Reader discretion is advised.
“I’m sorry, Art. What you’re asking for is illegal.”Continue reading
What if you could take a pill to enhance your cognitive abilities? What if this pill could help you ace a test, get more work done efficiently, and truly multitask? For entrepreneurs in Silicon Valley and executives on Wall Street, the answer to these questions is a resounding “Yes!” In these high stake environments, the use of nootropics, or “smart drugs,” by normal healthy people has become commonplace. But what exactly are the compounds that are claimed to improve brain function? And are they safe?Continue reading
What are brain waves? It’s no wonder the term sounds like science fiction. In the 1920s, a German psychiatrist embarked on a highly personal quest to discover the supposed medium of telepathy. By placing electrodes on the human scalp, Hans Berger found waves of electrical brain activity using a tool called electroencephalography, or EEG. Physicists had recently shown that electromagnetic waves could propagate through space to carry information. If the brain had its own waves, could they transmit thoughts to others like a radio broadcast?Continue reading