Resolving New Memories: Adult Neurogenesis by Knowing Neurons

Resolving New Memories: Adult Neurogenesis

When I was young, my family lived in an old farmhouse.  It was cozy and had a lot of character but, at over 150 years old, it showed its age.  My bedroom was unique since it had been updated with blue shag carpet sometime in the 1970’s.  It was also unique because there was a tiny nail that poked up through the floorboards a few inches past the doorway, hidden from view by the shag.  I knew exactly where that nail was though; I had stepped on it late one night and woke the house with my cries of pain!  Continue reading

Love is in the air! Or is that oxytocin?

Have you noticed the chocolates wrapped in bright red paper, teddy bears holding pink hearts in all the stores, and the endless supply of diamond commercials on television? Indeed, this Thursday is Valentine’s Day, which means couples will dote on each other with complete infatuation all day. But what happens after that lovely night out, when the alcohol is gone and the sugar high wears off? Will she notice the hot guys at the beach, and will his eyes wander to the attractive women walking across the street?Continue reading

“Free Bird:” How to Stay on Key

If you’ve ever done Karaoke, then you know how horribly some people sing, especially when the background music is too loud for them to hear themselves.  The ability to adjust to the environment is essential for all sensory systems, which use feedback mechanisms to modify behavior.  Usually the environmental cues are contaminated by noise, so your brain has to decide whether to modify behavior based on sensory feedback (and risk “adapting” to signals that do not accurately reflect performance) or to ignore sensory input (and risk leaving errors uncorrected).  So, how does your brain deal with this mismatch between the actual and expected sensory feedback, so you can have a better Karaoke performance?Continue reading

Towards A Better Brain Model

One of the fundamental goals of cognitive and systems neuroscience is to create a computer program that can simulate the activity of the human brain, from single neurons, through network level processing, to influences on behavior.  The only problem is that the human brain contains almost 90 billion neurons with an estimated total of 100 trillion synapses!  As staggeringly large as those numbers are, researchers actually aren’t too far away from producing such a complex computer program.Continue reading