Copy Number Variants: A Window into Psychiatric Illness

The human genome consists of nearly 25,000 protein-coding genes – and a mutation in just one of these can have dramatic effects on our brains.  Remarkably, one tiny change in our genes (which can be as small as 0.000000025 cm!) can lead to visible changes in our behavior.  Schizophrenia, autism, bipolar disorder, and ADHD have all been linked to variations in our DNA.  But how do changes in our genetic code result in these complex psychiatric disorders?Continue reading

Hacking your Brain with Smart Drugs

What if you could take a pill to enhance your cognitive abilities?  What if this pill could help you ace a test, get more work done efficiently, and truly multitask?  For entrepreneurs in Silicon Valley and executives on Wall Street, the answer to these questions is a resounding “Yes!”  In these high stake environments, the use of nootropics, or “smart drugs,” by normal healthy people has become commonplace.  But what exactly are the compounds that are claimed to improve brain function?  And are they safe?Continue reading

Brain Waves and Beta Buzz: The Wild Story of Neural Oscillations

What are brain waves?  It’s no wonder the term sounds like science fiction.  In the 1920s, a German psychiatrist embarked on a highly personal quest to discover the supposed medium of telepathy.  By placing electrodes on the human scalp, Hans Berger found waves of electrical brain activity using a tool called electroencephalography, or EEG.  Physicists had recently shown that electromagnetic waves could propagate through space to carry information.  If the brain had its own waves, could they transmit thoughts to others like a radio broadcast?Continue reading