Smells Like Teen Synapses: A Look Inside Adolescent Brains and Behaviors

Smells Like Teen Synapses: A Look Inside Adolescent Brains and Behaviors

“I would there were no age between sixteen and three-and-twenty, or that youth would sleep out the rest; for there is nothing in the between but getting wenches with child, wronging the ancientry, stealing, fighting…”

The old shepherd’s thoughts from Shakespeare’s A Winter’s Tale resonate centuries later when we consider examples of stereotypical teenage behavior – emotional outbursts, angst, and recklessness just to name a few.  But if we dismiss teenagers as lacking emotional discipline, we fail to understand the complex neural underpinnings that drive much of this behavior and allow a concerned adult to guide teens through this critical stage of brain development.Continue reading

Dendritic Spines Knowing Neurons

Keeping Memories Fresh by Keeping Glutamate In Check

We are another year older, perhaps a little wiser, and probably more forgetful.  Indeed, making memories is quite a process in the brain: specific synaptic connections are strengthened and new proteins are synthesized.  But as we age, the synapses that make up our memories, such as those in the hippocampus and prefrontal cortex, start to change and can be lost altogether.  The detrimental synaptic alterations may not be permanent, however, and maintaining the health of these synapses may be the key to preventing age-related cognitive decline.Continue reading