Brain Cigarette Knowing Neurons

The Strange Relationship between Nicotine and Parkinson’s Disease

According to the World Health Organization, smoking is responsible for approximately 6 million deaths in the world every year or one fatality every six seconds.  71% of all lung cancers and 42% of all chronic obstructive pulmonary diseases are attributable to tobacco use.  Oddly enough, not everything related to smoking is bad news: smokers seem to be protected against Parkinson’s disease.  Continue reading

CRISPR-Cas9 Knowing Neurons

CRISPR-Cas9: Targeted Genome Editing

CRISPR_Updated_FINAL_size

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Infographic by Jooyeun Lee and Kate Fehlhaber.

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References:

Hsu P. & Feng Zhang (2014). Development and Applications of CRISPR-Cas9 for Genome Engineering, Cell, 157 (6) 1262-1278. DOI: http://dx.doi.org/10.1016/j.cell.2014.05.010

Fineran P.C. (2014). Gene regulation by engineered CRISPR-Cas systems, Current Opinion in Microbiology, 18 83-89. DOI: http://dx.doi.org/10.1016/j.mib.2014.02.007

Doudna J.A. (2014). The new frontier of genome engineering with CRISPR-Cas9, Science, 346 (6213) 1258096-1258096. DOI: http://dx.doi.org/10.1126/science.1258096

From Turkey Comas To New Disease Treatments

Crystallography

Neurodegenerative disorders, like Huntington’s and Alzheimer’s disease, are devastating.  As you can imagine, witnessing the slow and progressive loss of a loved one’s mental and emotional states is an extremely painful and heartbreaking experience.  Currently, there are no cures for neurodegenerative diseases, and the drugs that are available only alleviate symptoms, without slowing the progression of the disease.Continue reading