Brain Waves and Beta Buzz: The Wild Story of Neural Oscillations

What are brain waves?  It’s no wonder the term sounds like science fiction.  In the 1920s, a German psychiatrist embarked on a highly personal quest to discover the supposed medium of telepathy.  By placing electrodes on the human scalp, Hans Berger found waves of electrical brain activity using a tool called electroencephalography, or EEG.  Physicists had recently shown that electromagnetic waves could propagate through space to carry information.  If the brain had its own waves, could they transmit thoughts to others like a radio broadcast?Continue reading

Teleportation! Hippocampal Oscillations during Navigation

Who hasn’t wanted to snap their fingers and dive into the pages of the gorgeous places featured in National Geographic?  Caught in a miserable physics exam that you haven’t studied for?  No problem, with teleportation you can be whisked away to an expedition to Mars or an Australian beach.  Afraid of heights but curious about skydiving?  Immersion into an artificial, computer-simulated environment can emulate the look and feel of the real thing without any danger or risk.  Virtual reality enables the military to train pilots to fly planes without leaving the safety of the base.  Virtual environments are almost limitless in scope, allowing researchers to study complex motor behaviors.  These virtual environments are often experienced with a head mounted display that allows the participant to move freely within the perceived environment — be it a pre-historic landscape or a lunar landing.Continue reading

Smooth Move: How GABAergic Interneurons Regulate Skilled Motor Behavior

In early 2014, the American free-solo rock climber Alex Honnold climbed 2,500 feet of limestone without ropes.  The demanding route called El Sendero Luminoso in El Potrero Chico, Mexico required 3 hours of intense concentration and precise movements. One wrong move and the young climber would have fallen thousands of feet with catastrophic consequences. In the video featured below, you see Honnold’s skilled movements and elegant displays of strength and precision. His ability to dramatically support his body weight with his fingertips and scale the wall like a spider monkey is due to the elaborate neural transformations that are directing each motor act.  The ability to perform an action like a climb is dependent on sensory feedback and refinement of local inhibitory microcircuits. Goal-directed reaching behavior depends on a hardwired control systems that underlies our capacity to smoothly execute movement.Continue reading