Mental Health is a Part of Health: A Conversation with Shekhar Saxena

In a recent presidential town hall, President Obama looked directly into the camera and made a powerful statement about mental health. “If something inside you feels like it’s wounded, it’s just like a physical injury. You’ve got to go get help,” said the leader of the free world.

Buried under the weight of a massive social stigma, seeking help or even acknowledging a mental illness can be an excruciating task. How, then, can we help ourselves and our loved ones achieve emotional and mental well-being?Continue reading

Learning from Disorder: The Paradox of Information in the Brain

In Dante’s Inferno, the fifth circle of Hell is a place where the wrathful fight each other for eternity.  Similarly, I often consider YouTube comments to be an extracanonical circle of Hell where the trolls fight each other for eternity.  You might, then, imagine my surprise when I found many thoughtful comments expressing wonder and intrigue on a YouTube video of brain activity in a zebrafish.  Continue reading

Science Advocacy on Capitol Hill: Bridging the Legislative Gap to Medical Research Funding

Last Thursday, September 17th I had the privilege of joining over 300 organizations including patients, physicians and fellow researchers in the Rally for Medical Research on Capitol Hill. Now in the third year of gathering to raise awareness for medical research, we met with Congressional representatives and staff from 40 states to demand “robust, sustainable and predictable funding increases for the NIH (National Institutes of Health)” in the coming fiscal year and beyond.Continue reading

Science Fiction, Serendipity and Interneuron Specification: A Conversation with Dr. Gordon J. Fishell

Gordon FishellIt is easy to assume that if a car has a gas pedal, it needs to have brakes, and similarly, if our brain has excitatory neurons, it needs inhibition too. For a long time, the field of neuroscience had thought of inhibitory interneurons as the “brakes” of the brain, providing suppression to neuronal activity. However, in my conversation with Dr. Gordon J. Fishell, I learned that interneurons are far more fascinating cell types than merely being inhibitory! Their multifarious morphology can be attributed to a palette of functions in brain developmental and regulation.Continue reading