CRISPR-Cas9 Knowing Neurons

CRISPR-Cas9: Targeted Genome Editing



Infographic by Jooyeun Lee and Kate Fehlhaber.



Hsu P. & Feng Zhang (2014). Development and Applications of CRISPR-Cas9 for Genome Engineering, Cell, 157 (6) 1262-1278. DOI:

Fineran P.C. (2014). Gene regulation by engineered CRISPR-Cas systems, Current Opinion in Microbiology, 18 83-89. DOI:

Doudna J.A. (2014). The new frontier of genome engineering with CRISPR-Cas9, Science, 346 (6213) 1258096-1258096. DOI:

New Microscope Helps Neuroscientists Ask New Questions

Last week, President Obama announced the Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative, a 10-year project to map the human brain.  President Obama introduced BRAIN as a way of encouraging neuroscientists to develop new technologies to study how neurons within the brain communicate with each other. New technologies are essential to helping neuroscientists ask new questions about how the brain works.  This project is similar to two other major projects: The Human Brain Project (European Union), which is working on a computer simulation of the entire brain, and The Human Connectome Project (National Institutes of Health) which is using state of the art magnetic resonance imaging (MRI) to track projections all over the brain.Continue reading