gene Archives - Knowing Neurons

Aging Did You Know?Learning and Memory Movement Neuro News

Kayleen Schreiber June 19, 2017June 30, 2017 Alzheimer’s disease, Brain, Cortex, DNA, Epigenetics, gene, Genetics, Infographic, Knowing Neurons, Learning, Memory, Nature, Nature Neuroscience, Neurodegeneration, Neuron, Neurons, Neuroscience, Prefrontal Cortex, Receptor, Research, Science

Bite-size Science: Epigenetics help protect the aging brain

Epigenetics change which genes are active and which are inactive. Research over the past few years has shown that these changes are important for protecting the brain from neurodegeneration and… Read More

Neurological and Psychiatric Disorders Did You Know?

Rachel Jonas September 21, 2016March 18, 2018 ADHD, Autism, Bipolar, Brain, CNV, Copy number variant, Deletion, DNA, gene, Genetics, Genome, LCR, Low copy repeat, Map, mutation, Population, Psychiatric, Schizophrenia, Syndrome

Copy Number Variants: A Window into Psychiatric Illness

The human genome consists of nearly 25,000 protein-coding genes – and a mutation in just one of these can have dramatic effects on our brains. Remarkably, one tiny change in… Read More

52 Brain Facts Sleep

knowingneurons July 4, 2016June 30, 2017 52 Brain Facts, Brain, Disease, Fatal Familial Insomnia, FFI, gene, Insomnia, Misfolded, mutation, Neurons, Prion, Protein, Sleep, Thalamus

Myth or Fact? A misfolded protein can cause you to never sleep again.

52 Brain Facts

knowingneurons June 13, 2016June 30, 2017 52 Brain Facts, Animal, Blue, Brain, Brainbow, connectome, Cool, Engineer, Engineering, Fact, Fluorescent, gene, genetic, Green, Image, Mice, Modification, Modified, Mouse, Rainbow, Red

Myth or Fact? Neurons can be genetically engineered to come in all colors of the rainbow.

Neuro News Did You Know?Learning and Memory

knowingneurons May 4, 2016March 5, 2017 Adrenal, Amygdala, Brain, cortisol, depression, Disorder, Early Life Adversity, ELA, Frontiers in Molecular Neuroscience, gene, Gland, glucocorticoid, glucose, Hippocampus, Iacoboni, Limbic, Maniam, Memory, Neurod1, Neurogenesis, Neuroplasticity, Plasticity, Psychotic, PTSD, Rats, Receptor, Spatial Navigation, stress, Sugar

Is too much sugar a form of brain abuse?

We all know too much sugar is bad for us. But did you know that having unfettered access to sugar might produce brain changes similar to highly stressful situations, such… Read More

52 Brain Facts

knowingneurons March 28, 2016April 3, 2016 52 Brain Facts, Biology, Brain, Chromosome, Disease, DNA, gene, Genetics, Manhattan, Method, Neuroscience, Plot, Scatter, Science, Significance, Skyline, SNP, Trait, Value

Myth or Fact? When geneticists talk about Manhattan, they don’t mean NYC.

Did You Know?Neuroscience Technologies

Jooyeun Lee March 18, 2015March 5, 2017 Animal model, Cas9, CRISPR, Disease, Disorder, DNA, Double-stranded break, Editing, Enzyme, gene, genetic, Genome, Infographic, Knock-in, Knock-out, KO, Mutagenesis, mutation, PAM, Replacement, Scissors, Targeted, Technique, Therapeutic

CRISPR-Cas9: Targeted Genome Editing

~ Infographic by Jooyeun Lee and Kate Fehlhaber. ~ References: Hsu P. & Feng Zhang (2014). Development and Applications of CRISPR-Cas9 for Genome Engineering, Cell, 157 (6) 1262-1278. DOI: http://dx.doi.org/10.1016/j.cell.2014.05.010 Fineran… Read More

Did You Know?Interviews SfN 2014

Jillian L. Shaw October 22, 2014March 5, 2017 and Synapses, Conversation, DNA, Eric Kandel, gene, Interview, Kelsey C. Martin, Kelsey Martin, Learning, M.D./Ph.D., Memory, Neurons, Peace Corps., Plasticity, SfN14, Synapse, Synapses, The Living Record of Memory: Genes, UCLA

From Stevens to Synapses: A Conversation with Kelsey Martin

[soundcloud url=”https://api.soundcloud.com/tracks/173263228″ params=”auto_play=false&hide_related=false&show_comments=true&show_user=true&show_reposts=false&visual=true” width=”100%” height=”450″ iframe=”true” /] Take your wildest guess. How many neurons make up the human brain? You’re not guessing wild enough if you said anything less than… Read More

(Transneuronal) Attack of the Mutant Huntingtin! Knowing Neurons

Did You Know?Movement Neurological and Psychiatric Disorders

Jillian L. Shaw September 17, 2014March 5, 2017 2014, Autosomal dominant, Botulinum neurotoxin, CAG, Chorea, Disorder, DNA, gene, Genetics, HD, HTT, Huntingtin, Huntington’s disease, mHTT, Movement, Nature Neuroscience, Trinucleotide repeat disorder

(Transneuronal) Attack of the Mutant Huntingtin!

Huntington’s disease (HD) is an incredibly debilitating neurodegenerative disorder. Currently, there is no treatment that effectively reverses the progression of the disease or delays its onset. Huntington’s is a particularly… Read More

Zinc finger nucleases: genomic scissors via Knowing Neurons

Did You Know?Neuroscience Technologies

Jooyeun Lee October 24, 2013March 5, 2017 AIDS, CCR5, Expression, Fok1, gene, Genetics, HIV, Homologous recombination, Infographic, mutation, Non-homologous end-joining, ZFN, zinc finger nuclease

Zinc Finger Nucleases: Genomic Scissors

The potential to manipulate DNA sequences and insert genes with the use of zinc finger nucleases (ZFNs) has huge implications for human genetic disease therapeutics. One exciting example is a… Read More

Movement Neurological and Psychiatric Disorders

Jillian L. Shaw November 16, 2012March 5, 2017 Bainbridge, Dopamine, DRD, dystonia, full genome sequencing, gene, genetic, human genome project, L-dopa, mutation, serotonin, SPR, Whole-Genome Sequencing for Optimized Patient Management

Unusual Suspects

More than a decade has passed since President Clinton first announced that the human genome project was successfully completed: We are here to celebrate the completion of the first survey… Read More