Genome Archives - Knowing Neurons

By Suhanee Mitragotri When your infant wakes up from a nap, all you want is to be able to hold them close and give them all of your love. While… Read More

Neurological and Psychiatric Disorders Did You Know?

Rachel Jonas September 21, 2016March 18, 2018 ADHD, Autism, Bipolar, Brain, CNV, Copy number variant, Deletion, DNA, gene, Genetics, Genome, LCR, Low copy repeat, Map, mutation, Population, Psychiatric, Schizophrenia, Syndrome

Copy Number Variants: A Window into Psychiatric Illness

The human genome consists of nearly 25,000 protein-coding genes – and a mutation in just one of these can have dramatic effects on our brains. Remarkably, one tiny change in… Read More

Did You Know?Neuroscience Technologies

Jooyeun Lee March 18, 2015March 5, 2017 Animal model, Cas9, CRISPR, Disease, Disorder, DNA, Double-stranded break, Editing, Enzyme, gene, genetic, Genome, Infographic, Knock-in, Knock-out, KO, Mutagenesis, mutation, PAM, Replacement, Scissors, Targeted, Technique, Therapeutic

CRISPR-Cas9: Targeted Genome Editing

~ Infographic by Jooyeun Lee and Kate Fehlhaber. ~ References: Hsu P. & Feng Zhang (2014). Development and Applications of CRISPR-Cas9 for Genome Engineering, Cell, 157 (6) 1262-1278. DOI: http://dx.doi.org/10.1016/j.cell.2014.05.010 Fineran… Read More