mutation Archives - Knowing Neurons

Melis Cakar August 1, 2022August 1, 2022 Attention, Fragile X, genes, Genetics, Hyperactivity, Learning Disability, mutation, Neurodevelopmental Disorder, Sensory Sensitivity, synaptic plasticity

Fragile X Syndrome

July is Fragile X awareness month. Learn more about Fragile X with our illustrator Melis Cakar’s new infographic!… Read More

Infographics A Close Up Look Big Ideas Neuro News Neuroscience Technologies

Gil Torten July 11, 2022July 11, 2022 cancer, cell count, Disease, DNA, mutation, Protein, RNA, Treatment, tumor

A Close Up Look 16 – scRNA-seq

In this new infographic, Gil Torten discusses single cell RNA sequencing (scRNA-seq). Read more to find out about what this process looks like and how scRNA-seq can be used in… Read More

Charcot-Marie-Tooth Disease (CMT) Feature Image

Infographics Movement Neurological and Psychiatric Disorders Sensation and Perception

Rajamani Selvam November 13, 2019November 13, 2019 Autosomal dominant, Autosomal Recessive, Charcot-Marie-Tooth Disease, Electromyogram, Genetic Mutation, Genetic Testing, Muscle Atrophy, mutation, myelin, Nerve Conduction Study, peripheral neuropathy, Sensory Loss, X-linked Dominant

Charcot-Marie-Tooth Disease [Infographic]

Charcot-Marie-Tooth disease is a peripheral neuropathy disorder that affects various genders and ethnic groups worldwide. Nerve cell abnormalities are associated with this disorder and are linked to symptoms such as… Read More

Neurological and Psychiatric Disorders Did You Know?

Rachel Jonas September 21, 2016March 18, 2018 ADHD, Autism, Bipolar, Brain, CNV, Copy number variant, Deletion, DNA, gene, Genetics, Genome, LCR, Low copy repeat, Map, mutation, Population, Psychiatric, Schizophrenia, Syndrome

Copy Number Variants: A Window into Psychiatric Illness

The human genome consists of nearly 25,000 protein-coding genes – and a mutation in just one of these can have dramatic effects on our brains. Remarkably, one tiny change in… Read More

52 Brain Facts Sleep

knowingneurons July 4, 2016June 30, 2017 52 Brain Facts, Brain, Disease, Fatal Familial Insomnia, FFI, gene, Insomnia, Misfolded, mutation, Neurons, Prion, Protein, Sleep, Thalamus

Myth or Fact? A misfolded protein can cause you to never sleep again.

Did You Know?Neuroscience Technologies

Jooyeun Lee March 18, 2015March 5, 2017 Animal model, Cas9, CRISPR, Disease, Disorder, DNA, Double-stranded break, Editing, Enzyme, gene, genetic, Genome, Infographic, Knock-in, Knock-out, KO, Mutagenesis, mutation, PAM, Replacement, Scissors, Targeted, Technique, Therapeutic

CRISPR-Cas9: Targeted Genome Editing

~ Infographic by Jooyeun Lee and Kate Fehlhaber. ~ References: Hsu P. & Feng Zhang (2014). Development and Applications of CRISPR-Cas9 for Genome Engineering, Cell, 157 (6) 1262-1278. DOI: http://dx.doi.org/10.1016/j.cell.2014.05.010 Fineran… Read More

Zinc finger nucleases: genomic scissors via Knowing Neurons

Did You Know?Neuroscience Technologies

Jooyeun Lee October 24, 2013March 5, 2017 AIDS, CCR5, Expression, Fok1, gene, Genetics, HIV, Homologous recombination, Infographic, mutation, Non-homologous end-joining, ZFN, zinc finger nuclease

Zinc Finger Nucleases: Genomic Scissors

The potential to manipulate DNA sequences and insert genes with the use of zinc finger nucleases (ZFNs) has huge implications for human genetic disease therapeutics. One exciting example is a… Read More

A World Without Pain Knowing Neurons Jillian Shaw Ouch

Did You Know?Neurological and Psychiatric Disorders Sensation and Perception

Jillian L. Shaw September 25, 2013March 5, 2017 2006, Al-Gazali, An SCN9A channelopathy causes congenital inability to experience pain, Cox, Dorsal Root Ganglia, Infographic, mutation, Nature, Nav1.7, Neuropathic, Nociceptor, Pain, SCN9A, Sodium channel, Somatosensory, Tetrodotoxin

A World Without Pain

In Northern Pakistan, a ten-year old street performer awed and horrified crowds with his ability to place knives through his arms and walk across burning coals all seemingly without pain.… Read More

Movement Neurological and Psychiatric Disorders

Jillian L. Shaw November 16, 2012March 5, 2017 Bainbridge, Dopamine, DRD, dystonia, full genome sequencing, gene, genetic, human genome project, L-dopa, mutation, serotonin, SPR, Whole-Genome Sequencing for Optimized Patient Management

Unusual Suspects

More than a decade has passed since President Clinton first announced that the human genome project was successfully completed: We are here to celebrate the completion of the first survey… Read More