Aging – Knowing Neurons

Aging Brain Basics Neuro Primer

Neuro Primer: Telomeres

noviembre 29, 2022noviembre 27, 2022 Marta Garo-Pascual 0 comentarios Aging, Alzheimer's, enfermedad de Alzheimer, cell division, Chromosome, DNA, Enzyme, Genetics, Neurodegeneration, Parkinson's, Parkinson's Disease, replication, telomerase, telomeres, Therapy

By Marta Garo-Pascual Telomeres are the “shoelace caps” of linear chromosomes and, as shoelace caps protect shoelaces, telomeres serve a protective role for chromosomes. Barbara McClintock and Hermann Muller described… Leer más

Aging Brain Development

Neuro Primer: Pubertal Timing

septiembre 12, 2022septiembre 10, 2022 Lauren Granata Anxiety, biological pathway, Childhood, Desarrollo, environmental influence, gonadotropins, Hormones, Hypothalamus, KNDy neurons, pituitary gland, puberty, estrés

By: Lauren Granata The transition from childhood to adulthood is notoriously turbulent. Teens fumble through these years as they try to finesse a balance between school, extracurriculars, and their ever-shifting… Leer más

Aging Cognición

Is Aging a Curable Disease?

agosto 9, 2022agosto 13, 2022 Arielle Hogan Aging, Animal research, anti-aging, cell environment, Cells, Central nervous system, cerebral spinal fluid, circulatory system, Cognitive Decline, CSF transfusion, Disease, DNA, gene expression, Longevity, Methylation, parabiosis, Progenitor Cell, White matter

By Arielle Hogan As you sit here reading this article, your cells are working away in your body performing all the diverse biochemical reactions necessary to keep you going. As… Leer más

Aging Infographics Multilingual Spanish

El Día de las Enfermedades Raras

mayo 14, 2022mayo 9, 2022 Arielle Hogan Enfermedad de Huntington, Enfermedad Rara, Esclerosis Lateral Amiotrófica, Síndrome de Rett

Traducido por Alba Peris-Yagüe… Leer más

Aging Cognición Aprendizaje y Memoria

¿Cambiará el nuevo medicamento para el Alzheimer nuestra forma de abordar esta enfermedad?

mayo 10, 2022junio 15, 2022 Marisa Guajardo enfermedad de Alzheimer, dementia, las drugas, dismunción de la memoria, tratamiento

Written by Diana Ortega Cruz In June of 2021, the US Food and Drug Administration (FDA) approved aducanumab, the first drug for the treatment of Alzheimer’s Disease (AD) that targets… Leer más

Aging Infographics Movement Neurological and Psychiatric Disorders

Knowing Parkinson’s Disease

abril 29, 2022abril 29, 2022 Arielle Hogan Aging, Bradykinesia, Dopamina, Neurodegeneration, Neurological Disorder, Parkinson's Disease

A Close Up Look Aging

A Close Up Look 13 – Aging

marzo 15, 2022marzo 14, 2022 Gil Torten Aging, degeneration, Epigenetics, Glaucoma, Senescence, Visión

In this new installment of our infographic series, A Close Up Look, KN Illustrator Gil Torten takes us on a journey through the affects of aging on vision. Check… Leer más

Studying Alzheimer’s Disease Using Open Data - Feature Image

Aging Big Ideas Aprendizaje y Memoria Science Policy

Studying Alzheimer’s Disease Using Open Data

noviembre 15, 2020diciembre 15, 2021 Arielle Hogan enfermedad de Alzheimer, Analysis, Data, Data Sharing, Meta-analysis, Open Data, Investigar

Open data sharing efforts can advance research by analyzing existing data for new trends and fostering collaborations across institutions and countries, which are especially useful for complex diseases such as… Leer más

Aging Big Ideas Aprendizaje y Memoria Neurological and Psychiatric Disorders

Can Hyperbaric Oxygen Therapy Delay Cognitive Decline?

octubre 6, 2020octubre 7, 2021 Charmi Porwal Age, Age-related cognitive decline, enfermedad de Alzheimer, Hyperbaric Oxygen Therapy, Metabolism, Oxygen

Mental abilities change throughout life, first as a result of brain maturation and later with the ageing of brain cells and their billions of complex interconnections. As we age, our… Leer más

Feature image depicting a fetus in the womb of a pregnant woman experiencing pain shortly after birth and having that pain show up later on in adulthood. Illustrated by McCall Sarrett.

Aging Big Ideas Brain Development Sensation and Perception

How Pain in Newborns Can Have Lifelong Consequences

septiembre 18, 2019septiembre 17, 2019 Denis Duagi Analgesics, Desarrollo cerebral, Chronic Pain, La electroencefalografía, o EEG,, Excitatory Neurons, Resonancia Magnética funcional, GABA, Glycine, Inhibitory Neurons, Neonatal Pain, Pain, Sensación, Somatosensory, Tactile fibers, Touch

You probably don’t remember anything from when you were an infant. However, chances are that you experienced some pain immediately after you were born. You might have needed an IV… Leer más

Aging Big Ideas Brain Development Aprendizaje y Memoria Sensation and Perception

Music for the Mind: How Music Nurtures Cognitive Development

febrero 28, 2019febrero 27, 2019 Alexandria Weaver auditory, Cognición, Desarrollo cognitivo, Emotion, Emotional Awareness, Aprendizaje, Listening, Memory, mood, Music, Musical Therapy, Performance, Therapy, Visuospatial abilities

Imagine listening to your favorite song, how it makes you feel, and the flood of memories the sounds bring with them. Music is well known for its ability to evoke… Leer más

Aging Aprendizaje y Memoria Neurological and Psychiatric Disorders Uncategorized

The Pathology of Alzheimer’s Disease

diciembre 6, 2018diciembre 5, 2018 Khayla Black Aging, Alzheimer's, enfermedad de Alzheimer, Amyloid beta, amyloid plaque, dementia, neurofibrillary tangles, Tau

Whether it be forgetting 20 years of your life or having the same conversation every five minutes only to forget it each time, memory impairment can take a large toll… Leer más

Aging Culture Neurological and Psychiatric Disorders

Food for Your Brain: Mediterranean Diet May Help Your Neurons Live Longer

noviembre 28, 2018noviembre 27, 2018 Marco Travaglio Aging, Alzeihmer's disease, Cerebro, dementia, dietary fat, Fat, Food, income, Aprendizaje, MeDi, Mediterranean Diet, Memory, Oxidative stress, socioeconomic status

Historians consider it one of the ‘cradles of civilization,’ but for many scientists today the real value of the Mediterranean basin does not lie in its contribution to history. Home… Leer más

Knowing Neurons - Artistic illustration of three different types of glial cells (astrocytes, microglia, oligodendrocytes)

Aging Brain Basics Brain Development Neuro Primer Neurological and Psychiatric Disorders

Neuro Primer: Glia

octubre 25, 2018octubre 25, 2018 Alexa Erdogan enfermedad de Alzheimer, Astrocyte, Ependymal cells, glia, homeostasis, Immune cells, Lou Gehrig's Disease, Microglia, Neuro Primer, Neurodegenerative disease, Neurodevelopment, Neuroglia, Neuroscience history, Neurotransmitters, Oligodendrocyte, Rene Dutrochet, Rudolf Virchow, Santiago Ramon y Cajal, Synapse, synaptic plasticity, Synaptogenesis

Every single day, a group of cells work tirelessly to monitor and protect the neural architecture of your brain. Some of them even move around, scanning neural networks like recon… Leer más

Neuro Primer: Aging Feature Image

Aging Brain Basics Neuro Primer Neurological and Psychiatric Disorders

Neuro Primer: Aging

octubre 10, 2018octubre 8, 2018 Gabrielle Torre AD, Age-related cognitive decline, Aging, ALS, Alzheimer's, enfermedad de Alzheimer, Amyloid, amyloid plaques, Baby Boomers, beta-amyloid, Brain activation, Brain cells, Cardiovascular health, Childhood, Cognición, Cognitive performance, Corteza, dementia, Disease, Executive function, Exercise, Genetics, glutamato, Hippocampus, Longevity, Memory, dismunción de la memoria, myelin, sistema nervioso, Neurogenesis, neuroimagen, Neuronas, Neuroplasticity, Neurociencia, Neurotransmitters, Normal aging, Parkinson's, Parkinson's Disease, Plasticity, Quality of life, Investigar, Science, Sleep, Sleep habits, Ventricles, Working memory

What happens to the brain in aging? Normal aging comes with many changes in brain structure and function. As individuals approach the age of 65 years and above, they experience… Leer más

Neuron Transplantation Cartoon

Out with the Old, in with the New – Can Neuron Transplantation Stop Brain Aging?

mayo 2, 2018mayo 2, 2018 Sophie Fessl Aging, cell replacement, cell transplantation, head transplantation, identity, organoid, Plasticity, Self

his past November, neurosurgeon Sergio Canavero connected a dead person’s head to a different corpse – a procedure he claimed to be a “successful head transplant.” His assertion was attacked by… Leer más

Aging Did You Know? Aprendizaje y Memoria Movement Neuro News

Bite-size Science: Epigenetics help protect the aging brain

junio 19, 2017junio 30, 2017 Kayleen Schreiber enfermedad de Alzheimer, Cerebro, Corteza, DNA, Epigenetics, gen, Genetics, Infographic, Knowing Neurons, Aprendizaje, Memory, Nature, Nature Neuroscience, Neurodegeneration, Neurona, Neuronas, Neurociencia, la corteza prefrontal, Receptor, Investigar, Science

Epigenetics change which genes are active and which are inactive. Research over the past few years has shown that these changes are important for protecting the brain from neurodegeneration and… Leer más

Smells Like Teen Synapses: A Look Inside Adolescent Brains and Behaviors

Aging Brain Development

Smells Like Teen Synapses: A Look Inside Adolescent Brains and Behaviors

noviembre 18, 2015marzo 5, 2017 knowingneurons Adolescent, Adult, Dendrite, Dendritic spine, Desarrollo, Emotion, Mindfulness, Plasticity, la corteza prefrontal, Ronald Dahl, Synaptogenesis, Teenager, Teens, Ventral striatum

“I would there were no age between sixteen and three-and-twenty, or that youth would sleep out the rest; for there is nothing in the between but getting wenches with child,… Leer más

Dendritic Spines Knowing Neurons

Aging Aprendizaje y Memoria Neuro News

Keeping Memories Fresh by Keeping Glutamate In Check

enero 21, 2015marzo 5, 2017 Kate Fehlhaber 2014, Aging, enfermedad de Alzheimer, Dendrite, glutamato, Glutamatergic, Hippocampus, Long-term potentiation, LTP, Memory, Morrison, Neuroplasticity, Pereira, PNAS, la corteza prefrontal, Riluzole, Spine

We are another year older, perhaps a little wiser, and probably more forgetful. Indeed, making memories is quite a process in the brain: specific synaptic connections are strengthened and new… Leer más

Your Brain Breathes Too by Knowing Neurons

Aging Neuro News Neurological and Psychiatric Disorders

Your Brain Breathes Too

enero 29, 2014marzo 5, 2017 knowingneurons Aging, Air pollution, BBB, Blood-brain barrier, Cerebro, Breathe, Cell death, Dysfunction, Epidemiological, Los Angeles, Lungs, Neurotoxicity, Neurotoxocology, Oxidative stress, Pollution, Smog, Tight junctions

I live in Los Angeles and it’s unfortunate, but true, that the brown cloud of smog hanging over our city is as much an icon of LA as the Hollywood… Leer más

Sweet Dreams or Amyloid Nightmares by Knowing Neurons

Aging Did You Know? Neurological and Psychiatric Disorders Sleep

Sweet Dreams or Amyloid Nightmares

noviembre 7, 2013marzo 5, 2017 Jillian L. Shaw enfermedad de Alzheimer, Amyloid beta, amyloid-β plaques, Biomarcador, circadian clock, circadian rhythm, David Holtzman, dementia, Disruption of the sleep-wake cycle and diurnal fluctuation of beta-amyloid in mice with Alzheimer's disease pathology, Hippocampus, Jee Hoon Roh, Memory, Microdialysis, Science Translational Medicine, Sleep

Sleep deprivation has become a badge of honor in our modern society. Competitions break out in coffee shop lines over who is functioning on the least number of Zzzzzs and… Leer más

Aging Aprendizaje y Memoria Neuro News Neurological and Psychiatric Disorders

Magnesium Supplement to Treat Alzheimer’s Disease

mayo 27, 2013marzo 5, 2017 Ryan Jones AD, AD-mice, Age, Aging, Alzheimer's, enfermedad de Alzheimer, and Synaptic Plasticity in the Infralimbic Prefrontal Cortex and Lateral Amygdala, dementia, Effects of Elevation of Brain Magnesium on Fear Conditioning, Elderly, Elevation of Brain Magnesium Prevents and Reverses Cognitive Deficits and Synaptic Loss in Alzheimer's Disease Mouse Model, Emotion, Enhancement of Learning and Memory by Elevating Brain Magnesium, Enhancement of Synaptic Plasticity through Chronically Reduced Ca2+ Flux during Uncorrelated Activity, Fear Extinction, Journal of Neuroscience, Aprendizaje, Liu, Magnesium, Memory, Mg2+, MIT, Neurona, NMDA, NMDA receptors, Old, Slutsky, Supplement, Synapse, Synaptic function, Synaptic loss

The human brain contains roughly eighty-six billion (~10^10) neurons, each of which forms approximately ten thousand (10^4) synaptic connections with other neurons. Therefore, on average, there are one hundred trillion… Leer más

Aging Brain Development Aprendizaje y Memoria Neuro News

Brain Changes for Sculpted, Efficient Memory

enero 28, 2013marzo 5, 2017 JuanVelasquez 2013, Hippocampus, Increased NR2A:NR2B ratio compresses long-term depression range and constrains long-term memory, Aprendizaje, LTD, LTP, Memory, NMDA, NR2A, NR2B

While I was growing up, I remember my parents and teachers saying, “Your brain is like a sponge.” Of course, I didn’t understand what they meant, but as cliché as… Leer más

Aging Brain Basics Brain Development Did You Know? Neurological and Psychiatric Disorders

Mitochondria: More Than Just a Powerhouse

enero 23, 2013marzo 5, 2017 JuanVelasquez Adaptive Downregulation of Mitochondrial Function in Down Syndrome, enfermedad de Alzheimer, Autismo, Down syndrome, Energy Failure, Mitochondrial Dysfunction, Parkinson's Disease

Mitochondria are frequently implicated in several human disease states. From neurological disorders like Alzheimer’s disease and Autism Spectrum Disorder, to metabolic conditions like diabetes and obesity, energy abnormalities are seen… Leer más

Aging Neuro News Neurological and Psychiatric Disorders

When Cellular Power Plants Fail

enero 21, 2013marzo 5, 2017 Jooyeun Lee Adaptive Downregulation of Mitochondrial Function in Down Syndrome, enfermedad de Alzheimer, Cell Metabolism, Down syndrome, Jorge Busciglio, mitochondria, Oxidative stress, Pablo Helguera, Reactive oxygen species, Trisomy 21

Humans normally have 23 pairs of chromosomes, but sometimes an error during cell division causes there to be an abnormal number of chromosomes. One of the most common chromosome abnormalities… Leer más

Aging Movement Neuro News Neurological and Psychiatric Disorders

Treating the diseased brain with artificial stimulation

enero 14, 2013marzo 5, 2017 Anita Antidromic spikes, Basal ganglia, DBS, Deep Brain Stimulation, Dopamina, Neurona, Parkinson's Disease, Qian Li, Substantia Nigra, Subthalamic nucleus, Therapeutic deep brain stimulation in parkinsonian rats directly influences motor cortex., Wing-Ho Yung

We often fail to appreciate the small and precise functions of our motor system. How effortless and smooth our movements are when getting up from a chair! How quick and… Leer más

Aging Did You Know? Aprendizaje y Memoria

Leisure for the Body. Labor for the Brain.

noviembre 28, 2012marzo 5, 2017 Anita Activity, Aging, Cognitive Reserve and Lifestyle, Leisure, Memory, Scarmeas

What do you do when you take a break from work? In your leisure time, what is something that you routinely find yourself doing? What is your default solution to… Leer más

Aging Brain Basics Did You Know? Neurological and Psychiatric Disorders

A Close Look into the Alzheimer’s Brain

noviembre 21, 2012marzo 5, 2017 JuanVelasquez aggregate, Alzheimer's, amyloid-beta plaques, atrophy, Cerebro, CT, dementia, mitochondria, neurobiology, neurofibrillary tangles, Neurociencia, pathology, TEP

Your brain is able to store massive amounts of memories throughout your lifetime. There are cases, however, in which this ability progressively degrades and eventually disappears, giving way to problems… Leer más

Aging Aprendizaje y Memoria Neuro News Neurological and Psychiatric Disorders

Solving the Alzheimer’s Puzzle: One Piece at a Time

noviembre 19, 2012marzo 5, 2017 Anita AD, Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons, Alzheimer's, amyloid-β, cellular prion protein, kinase-signaling, lactate dehydrogenase, Nature Neuroscience, NMDA receptors, Strittmatter, synaptic plasticity

Based on the recent statistics, one in eight individuals over the age of 65 has Alzheimer’s disease, and for every 68 seconds that pass, yet another individual in the United… Leer más