Disease Archives - Knowing Neurons

Neuro Primer: Aging

October 10, 2018October 8, 2018 Gabrielle Torre 0 Comments AD, Age-related cognitive decline, Aging, ALS, Alzheimer's, Alzheimer’s disease, Amyloid, amyloid plaques, Baby Boomers, beta-amyloid, Brain activation, Brain cells, Cardiovascular health, Childhood, Cognition, Cognitive performance, Cortex, dementia, Disease, Executive function, Exercise, Genetics, glutamate, Hippocampus, Longevity, Memory, Memory decline, myelin, Nervous System, Neurogenesis, Neuroimaging, Neurons, Neuroplasticity, Neuroscience, Neurotransmitters, Normal aging, Parkinson's, Parkinson's Disease, Plasticity, Quality of life, Research, Science, Sleep, Sleep habits, Ventricles, Working memory

What happens to the brain in aging? Normal aging comes with many changes in brain structure and function. As individuals approach the age of 65 years and above, they experience… Read more

Brain Basics Neurological and Psychiatric Disorders Sleep

The inescapable nightmare of fatal familial insomnia

October 31, 2017October 31, 2017 Sean Noah 1 Comment Brain, Cortex, Disease, Disorders, Fatal Familial Insomnia, FFI, Genetics, Insomnia, Molecular neuroscience, Neuroscience, Prions, Psychiatry, Sleep, Sleep disorders

A family curse During the early 1980’s, an Italian physician was investigating a mysterious and dreadful disease that had long plagued his family. In earlier generations, this disease had killed… Read more

Did You Know? Movement Weird Animal Brain

Weird animal brain: Jewel wasp

September 19, 2016June 30, 2017 Kayleen Schreiber 3 Comments Brain, Bug, Cockroach, Disease, Fact, Infographic, Insect, Knowing Neurons, Neurons, Neuroscience, Pain, Science, Wasp, Weird Animal Brain

The jewel wasp’s venom is potent on two levels. … Read more

52 Brain Facts Sleep

Myth or Fact? A misfolded protein can cause you to never sleep again.

July 4, 2016June 30, 2017 knowingneurons 0 Comments 52 Brain Facts, Brain, Disease, Fatal Familial Insomnia, FFI, gene, Insomnia, Misfolded, mutation, Neurons, Prion, Protein, Sleep, Thalamus

Movement Neuro News

The Strange Relationship between Nicotine and Parkinson’s Disease

April 13, 2016March 5, 2017 knowingneurons 5 Comments 2016, Aggregates, Block, Bradykinesia, Brain, Cell, Cell death, Chaperone, Clusters, Disease, Disorder, Dopamine, Drug, Exercise, Inhibit, Lester, Misfolded, Movement, Neuroscience, News, Nicotine, Nigrostriatal pathway, Parkinson's Disease, PD, Protection, Protein, Protein folding, Reward pathway, Smoking, Smoking-Relevant Nicotine Concentration Attenuates the Unfolded Protein Response in Dopaminergic Neurons, Srinivasan, Tunycamycin

According to the World Health Organization, smoking is responsible for approximately 6 million deaths in the world every year or one fatality every six seconds. 71% of all lung cancers… Read more

52 Brain Facts

Myth or Fact? When geneticists talk about Manhattan, they don’t mean NYC.

March 28, 2016April 3, 2016 knowingneurons 0 Comments 52 Brain Facts, Biology, Brain, Chromosome, Disease, DNA, gene, Genetics, Manhattan, Method, Neuroscience, Plot, Scatter, Science, Significance, Skyline, SNP, Trait, Value

Did You Know? Neurological and Psychiatric Disorders Sleep

Melatonin: An Old Hormone with New Tricks

December 2, 2015March 5, 2017 knowingneurons 0 Comments Autoimmune, Circadian, Clock, Disease, EAE, experimental autoimmune encephalomyelitis, Inflammation, interleukin, melatonin, MS, multiple sclerosis, Neuroinflammation, Pineal gland, Rhythm, Season, T cell

Melatonin: you’ve undoubtedly seen it in the supplement aisle at the drugstore…that natural sleep remedy your aunt recommended once, sounding vaguely like a portmanteau of mellow and serotonin. But between… Read more

Did You Know? Neuroscience Technologies

CRISPR-Cas9: Targeted Genome Editing

March 18, 2015March 5, 2017 Jooyeun Lee 1 Comment Animal model, Cas9, CRISPR, Disease, Disorder, DNA, Double-stranded break, Editing, Enzyme, gene, genetic, Genome, Infographic, Knock-in, Knock-out, KO, Mutagenesis, mutation, PAM, Replacement, Scissors, Targeted, Technique, Therapeutic

~ Infographic by Jooyeun Lee and Kate Fehlhaber. ~ References: Hsu P. & Feng Zhang (2014). Development and Applications of CRISPR-Cas9 for Genome Engineering, Cell, 157 (6) 1262-1278. DOI: http://dx.doi.org/10.1016/j.cell.2014.05.010 Fineran… Read more

Neuro News Neurological and Psychiatric Disorders Sleep

From Turkey Comas To New Disease Treatments

April 22, 2013March 5, 2017 Kate Fehlhaber 0 Comments 2013, Alzheimer's, Amino acid, BBB, Blood-brain barrier, Crystallography, Disease, Drug, Huntington's, KMO, Metabolism, Nature, Neurodegeneration, Neurodegenerative disease, Sleep, Structural basis of kynurenine 3-monooxygenase inhibition, Target, Therapy, Tryptophan, UPF648

Neurodegenerative disorders, like Huntington’s and Alzheimer’s disease, are devastating. As you can imagine, witnessing the slow and progressive loss of a loved one’s mental and emotional states is an extremely… Read more

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