Excitation and Inhibition: The Yin and Yang of the Brain

To make a working nervous system, only two forces are necessary: excitation and inhibition.… Read more

Smooth Move: How GABAergic Interneurons Regulate Skilled Motor Behavior

In early 2014, the American free-solo rock climber Alex Honnold climbed 2,500 feet of limestone without ropes.  The demanding route called El Sendero Luminoso in El Potrero Chico, Mexico required… Read more

Science Fiction, Serendipity and Interneuron Specification: A Conversation with Dr. Gordon J. Fishell

It is easy to assume that if a car has a gas pedal, it needs to have brakes, and similarly, if our brain has excitatory neurons, it needs inhibition too.… Read more
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