Schizophrenia in a Vial? The Story of Ketamine

Note: Ketamine is a controlled substance in the US and many other countries. Do not use ketamine illicitly. magine an injection that briefly gives you schizophrenia. Now imagine that this… Read more

Excitation and Inhibition: The Yin and Yang of the Brain

To make a working nervous system, only two forces are necessary: excitation and inhibition.… Read more

Keeping Memories Fresh by Keeping Glutamate In Check

We are another year older, perhaps a little wiser, and probably more forgetful.  Indeed, making memories is quite a process in the brain: specific synaptic connections are strengthened and new… Read more

Science Fiction, Serendipity and Interneuron Specification: A Conversation with Dr. Gordon J. Fishell

It is easy to assume that if a car has a gas pedal, it needs to have brakes, and similarly, if our brain has excitatory neurons, it needs inhibition too.… Read more

A Piece of Licorice a Day Keeps the Doctor Away?

Turns out that tub of black licorice you got from Costco, and managed to eat in only a few days (don’t worry, I won’t tell anybody!), might have actually done… Read more

From Neurons to Astrocytes: The Shift of Focus in Stroke

If you think about it, blood vessels are the freeways of the body. The vast array of vasculature enables molecules to reach important destinations (organs) quickly. But, if a small… Read more
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